CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity Appearance:Solid IC50& Target:CRBN-DDB1 490 nM (IC 50 ) In Vitro:CCT367766 formic (50-1500 nM; 24 hours) demonstates the depletion of pirin protein as a the time-dependent hook-effect in SK-OV-3 human ovarian cancer cells. CCT367766 formic (0.5-50 nM; 2 hours) demonstrates the concentration-dependent depletion of Biological Activity:CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity
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CCT367766 formic
CAS number：unknown molecular formula：C50H50ClN7O13
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| Chinese alias | CCT367766 甲酸 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C50H50ClN7O13 |
| molecular weight | 992.42 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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