CAS number：873080-25-2 molecular formula：C19H17Cl2N3O4S
ZAP-180013 是一种 ZAP-70 抑制剂，IC50 为 1.8 μM。ZAP-180013 抑制 ZAP-70 SH2 结构域与基于免疫受体酪氨酸的激活基序 (ITAM) 的相互作用。 Product description ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs).
| Chinese alias | 5-氯-N-[(4-氯苯基)甲基] -2-(乙基磺酰基)-N-(2-呋喃基甲基)-4-嘧啶甲酰胺 | ||
| English alias | 5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide | ||
| CAS number | 873080-25-2 | molecular formula | C19H17Cl2N3O4S |
| molecular weight | 454.32 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | - | logp | - |
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