L-368,899 hydrochloride 是一种有效的,选择性的,可口服的,非肽类催产素受体 oxytocin receptor 拮抗剂,对大鼠和人子宫 oxytocin receptor 的 IC50 值分别为 8.9 nM 和 26 nM,为抗早产剂。 L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent.
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L-368,899 hydrochloride
CAS number:160312-62-9 molecular formula:C26H42N4O5S2.HCl
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| Chinese alias | (2S)-2-氨基-N-[(1S,2S,4R)-7,7-二甲基-1-[[[4-(2-甲基苯基)-1-哌嗪基]磺酰基]甲基]双环[2.2。 1]庚-2-基] -4-(甲基磺酰基)丁酰胺 | ||
| English alias | (2S)-2-Amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)butanamide | ||
| CAS number | 160312-62-9 | molecular formula | C26H42N4O5S2.HCl |
| molecular weight | 591.23 g/mol | Exact mass | ≥97% |
| PSA | - | logp | - |
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