(+)-JQ1 PA 是溴结构域和额外末端结构域 (BET) 抑制剂 JQ1 的衍生物,其 IC50 值为 10.4 nM。
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(+)-JQ1 PA
CAS number:2115701-93-2 molecular formula:C22H20ClN5OS
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compound introduction
Specs
| Chinese alias | (6S)-4-(4-氯苯基)-2,3,9-三甲基-N-2-丙炔-1-基-6H-噻吩并[3,2-f] [1,2,4]三唑[4 ,3-a] [1,4]二氮杂6-乙酰胺 | ||
| English alias | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-N-2-propyn-1-yl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide | ||
| CAS number | 2115701-93-2 | molecular formula | C22H20ClN5OS |
| molecular weight | 437.95 g/mol | Exact mass | ≥95%(HPLC) |
| PSA | 100.000 Ų | logp | 3.4 |
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