CAS number：2364489-81-4 molecular formula：C28H30Cl3N7O5S
FMF-04-159-2 是一种有效的共价 CDK14 抑制剂。FMF-04-159-2 抑制 CDK14 和 CDK2，在 NanoBRET 试验中 IC50 分别为 39.6 nM 和 256 nM。 Product description： FMF-04-159-2 is a covalent CDK14 inhibitor. FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively.
| Chinese alias | N-[1-[[3-[[((2E)-4-(二甲基氨基)-1-氧-2-丁烯-1-基]氨基]苯基]磺酰基] -4-哌啶基] -4-[(2 ,4,6-三氯苯甲酰基)氨基] -1H-吡唑-3-羧酰胺 | ||
| English alias | (E)-N-(1-((3-(4-(dimethylamino)but-2-enamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide | N-[1-[[3-[[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)am | ||
| CAS number | 2364489-81-4 | molecular formula | C28H30Cl3N7O5S |
| molecular weight | 683.01 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | - | logp | - |
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