compound introduction
IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent I K1 (K IR 2.x ion-channel-carried inward rectifier current) inhibitor, with IC 50 values of 12-15 nM for human and mouse K IR 2.x currents. IK1 inhibitor PA-6 (PA-6) elevates K IR 2.1 protein expression and induces intracellular K IR 2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia Form:Solid IC50& Target:IC50: 12-15 nM (K IR 2.x currents)
