CAS number：915365-57-0 molecular formula：C27H27Cl2FN8
Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC 50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC 50 of 5.7 nM Form:Solid IC50& Target:IC50: 28 nM (Tpl2 kinase)
| Chinese alias | Cot抑制剂-1 | ||
| English alias | - | ||
| CAS number | 915365-57-0 | molecular formula | C27H27Cl2FN8 |
| molecular weight | 553.46 g/mol | Exact mass | ≥98% |
| PSA | 94.700 Ų | logp | 5.800 |
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