compound introduction
GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects. In Vivo GPR30 agonist-1 (compound 5408-0877) (1 nM-10 μM) induces a concentration-dependent relaxation in carotid arteries from both male and female rats. GPR30 agonist-1-induced relaxation is abolished by endothelium removal and abrogated in the presence of the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester (100 μM) . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
