IDO1/2-IN-1 hydrochloride (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC 50 s of 28 nM and 144 nM for IDO1 and IDO2 , respectively. IDO1/2-IN-1 hydrochloride exhibits antitumor activies. Orally active.
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IDO1/2-IN-1 hydrochloride
CAS number:2310286-60-1 molecular formula:C16H19BrClFN8O4
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| Chinese alias | IDO1/2-IN-1盐酸盐 | ||
| English alias | - | ||
| CAS number | 2310286-60-1 | molecular formula | C16H19BrClFN8O4 |
| molecular weight | 521.73 g/mol | Exact mass | - |
| PSA | - | logp | - |
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