Information DS-1971a is a potent, selective, and orally active inhibitor of NaV1.7 with IC50 of 22.8 nM and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects.
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DS-1971a
CAS number:1450595-86-4 molecular formula:C20H21ClFN5O3S
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| Chinese alias | - | ||
| English alias | 5-Chloro-2-fluoro-4-{[(1S,2R)-2-(1-methyl-1H-pyrazol-5-yl)cyclohexyl]oxy}-N-(pyrimidin-4-yl)benzenesulfonamide | US9493448, 48 | EX-A4272 | compound 6o [PMID: 32392056] | MS-28586 | UNII-EHV5F71MBF | HY-131182 | 5-Chloro-2-fluoro-4-(((1S,2R)-2-(1-methyl-1 | ||
| CAS number | 1450595-86-4 | molecular formula | C20H21ClFN5O3S |
| molecular weight | 465.93 g/mol | Exact mass | - |
| PSA | 107.000 Ų | logp | 3.3 |
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