compound introduction
PF-05186462 是一种有效和选择性的人Nav1.7电压依赖性钠通道抑制剂，IC50值为 21 nM。PF-05186462 对 Nav1.7 与其他钠通道 (Nav 1.1、1.2、1.3、1.4、1.5、1.6 和 1.8) 相比显示出显着的选择性。PF-05186462 可用于急性或慢性疼痛的研究。
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Benzenesulfonamide, 5-chloro-2-fluoro-4-[2-(4-pyridazinyl)-4-(trifluoromethyl)phenoxy]-N-1,3,4-thiadiazol-2-yl-
CAS number：1235406-03-7 molecular formula：
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1235406-03-7 | molecular formula | |
| molecular weight | 531.900 g/mol | Exact mass | ≥99% |
| PSA | 144.000 Ų | logp | 3.9 |
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