compound introduction
RXDX-106 (CEP-40783)是一种有效的、选择性的TAM(TYRO3, AXL, MER)/Met (c-Met)抑制剂，在肽段磷酸化实验中具有较低的纳摩尔级别生化活性；在体外激酶结合试验中具有慢速的解离率（T1/2 >120 min）
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CEP-40783
CAS number：1437321-24-8 molecular formula：C31H26F2N4O6
overview
Specs
| Chinese alias | - | ||
| English alias | AS-35141 | N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide | CEP 40783 | UNII-1969ZJE05Q | 1969ZJE05Q | HY-100946 | s8570 | EX-A2540 | 1437321-24-8 | CEP40783 | CEP | ||
| CAS number | 1437321-24-8 | molecular formula | C31H26F2N4O6 |
| molecular weight | 588.6 g/mol | Exact mass | 10mM in DMSO |
| PSA | 110.000 Ų | logp | 4.700 |
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