SRI 31215 是 matriptase、hepsin、肝细胞生长因子激活剂(HGFA)的三重抑制剂,IC50值分别为 0.69 μM、0.65 μM、0.3 μM。它能够阻断 pro-HGF 的活化,模拟 HAI-1/2 的活性。 SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 μM, 0.65 μM, 0.3 μM.
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SRI 31215 TFA
CAS number:1832686-44-8 molecular formula:C27H34F3N5O3
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| Chinese alias | - | ||
| English alias | SRI 31215 | ||
| CAS number | 1832686-44-8 | molecular formula | C27H34F3N5O3 |
| molecular weight | 533.59 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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