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SRI 31215 TFA

CAS number:1832686-44-8    molecular formula:C27H34F3N5O3

overview

compound introduction

SRI 31215 是 matriptase、hepsin、肝细胞生长因子激活剂(HGFA)的三重抑制剂,IC50值分别为 0.69 μM、0.65 μM、0.3 μM。它能够阻断 pro-HGF 的活化,模拟 HAI-1/2 的活性。 SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 μM, 0.65 μM, 0.3 μM.

Specs

Chinese alias-
English aliasSRI 31215
CAS number1832686-44-8molecular formulaC27H34F3N5O3
molecular weight533.59 g/molExact mass≥98%
PSA-logp-

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