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Bozitinib (PLB-1001)

CAS number:1440964-89-5    molecular formula:C20H15F3N8

overview

compound introduction

Information Bozitinib (PLB-1001) Bozitinib (PLB-1001, CBT-101, APL-101, CBI-3103) is a highly selective ATP-competitive c-Met inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) selectively inhibits MET-altered tumor cells in preclinical models. Targets c-Met

Specs

Chinese alias-
English alias1,2,4-Triazolo(4,3-b)pyridazine, 6-(1-cyclopropyl-1H-pyrazol-4-yl)-3-(difluoro(6- fluoro-2-methyl-2H-indazol-5-yl)methyl)- | 6-(1-Cyclopropyl-1H-pyrazol-4-yl)-3-(difluoro(6-fluoro-2-methyl-2H-indazol-5-yl)methyl)-[1,2,4]triazolo[4,3-b]pyridazine | UNII-2W
CAS number1440964-89-5molecular formulaC20H15F3N8
molecular weight424.38 g/molExact mass-
PSA78.700 Ųlogp3.548

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