compound introduction
AMG 925 是一种选择性FLT3/CDK4双重抑制剂，IC50分别为 1 nM 和 3 nM Information AMG 925 AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively. Targets FLT3 ; CDK4 1 nM; 3 nM
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AMG 925
CAS number：1401033-86-0 molecular formula：C26H29N7O2
overview
Specs
| Chinese alias | - | ||
| English alias | AMG 925 | AMG925 | AMG-925 | NSC781514 | NSC-781514 | AS-17036 | J-018057 | FLX925 (AMG-925) | RB6Y814V4I | Ethanone, 1-(7,8-dihydro-2-((9-(trans-4-methylcyclohexyl)-9H-pyrido(4',3':4,5)pyrrolo(2,3-d)pyrimidin-2-yl)amino)-1,6-naphthyridin-6(5H)-yl)-2-hydr | ||
| CAS number | 1401033-86-0 | molecular formula | C26H29N7O2 |
| molecular weight | 471.55 g/mol | Exact mass | ≥98% |
| PSA | 109.000 Ų | logp | 2.7 |
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