CAS number：1256580-46-7 molecular formula：C30H34N4O2
Alectinib (CH5424802)是一种有效的ALK抑制剂，IC50为1.9 nM，对L1196M突变型敏感，作用于ALK比PF-02341066， NVP-TAE684和PHA-E429选择性高。An ATP-competitive inhibitor for ALK and L1196M. Alectinib (CH5424802) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429 An ATP-competitive inhibitor for ALK and L1196M.
| Chinese alias | - | ||
| English alias | AF 802 | SR-01000389722-2 | 9-ETHYL-6,6-DIMETHYL-8-[4-(MORPHOLIN-4-YL)PIPERIDIN-1-YL]-11-OXO-5H,6H,11H-BENZO[B]CARBAZOLE-3-CARBONITRILE | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile | Al | ||
| CAS number | 1256580-46-7 | molecular formula | C30H34N4O2 |
| molecular weight | 482.62 g/mol | Exact mass | - |
| PSA | 72.400 Ų | logp | 5.200 |
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