Zoligratinib (Debio 1347) 是口服可用,选择性的 FGFR 抑制剂,抑制FGFR1,FGFR2和 FGFR3的IC50 值分别为9.3,7.6,22 and 290 nM
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CH5183284 (Debio-1347)
CAS number:1265229-25-1 molecular formula:C20H16N6O
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| Chinese alias | - | ||
| English alias | (5-amino-1-(2-methyl-3H-benzo[d]imidazol-5-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone | CH5183284; Debio-1347 | GTPL9787 | EX-A1122 | NR9ZYH80Z8 | A901067 | AC-32960 | ZOLIGRATINIB [WHO-DD] | Debio 1347 | HY-19957 | Salicylic acid, {5-[[p-[(p-sulfopheny | ||
| CAS number | 1265229-25-1 | molecular formula | C20H16N6O |
| molecular weight | 356.38 g/mol | Exact mass | - |
| PSA | 105.000 Ų | logp | 3.9 |
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