CAS number：1415823-73-2 molecular formula：C25H27N5O2
Information Evobrutinib (M-2951) Evobrutinib (M-2951, MSC-2364447C) is a highly selective BTK inhibitor with an IC50 of 37.9 nM. It has potential anti-neoplastic activity. Targets BTK (Cell-free assay) 37.9 nM In vitro Evobrutinib can inhibit the activity of BTK and prevent the activation of the BCR signaling pathway. It is metabolized via hydroxylation, hydrolysis, O-dealkylation, glucuronidation, and GSH conjugation.
| Chinese alias | 依沃布替尼 (M-2951) | ||
| English alias | DB15170 | EX-A2691 | 1-(4-(((6-Amino-5-(4-phenoxyphenyl)-4-pyrimidinyl)amino)methyl)-1-piperidinyl)-2-propen-1-one | BCP28995 | SCHEMBL14165673 | GTPL9752 | 1-[4-[[[6-amino-5-(4-phenoxyphenyl)-4-pyrimidinyl]amino]methyl]-1-piperidinyl]-2-propen-1-one | EV | ||
| CAS number | 1415823-73-2 | molecular formula | C25H27N5O2 |
| molecular weight | 429.51 g/mol | Exact mass | - |
| PSA | 93.400 Ų | logp | 4.2 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
