CAS number：1421502-62-6 molecular formula：C31H31FN8O2
PF-06263276 (PF 6263276) is a potent and selective pan-JAK inhibitor, with IC 50 s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1 , JAK2 , JAK3 and TYK2 , respectively Form:Solid IC50& Target:JAK1 2.2 nM (IC 50 ) JAK2 23.1 nM (IC 50 ) JAK3 59.9 nM (IC 50 ) Tyk2 29.7 nM (IC 50 )
| Chinese alias | - | ||
| English alias | SCHEMBL20767494 | PF-06263276 | 7GS | {2-[6-(2-Ethyl-5-Fluoro-4-Hydroxyphenyl)-2h-Indazol-3-Yl]-3,4,6,7-Tetrahydro-5h-Imidazo[4,5-C]pyridin-5-Yl}[5-(Piperidin-1-Yl)pyrazin-2-Yl]methanone | SCHEMBL14658676 | (2-(6-(2-Ethyl-5-fluoro-4-hydroxyphenyl)-1H-inda | ||
| CAS number | 1421502-62-6 | molecular formula | C31H31FN8O2 |
| molecular weight | 566.63 g/mol | Exact mass | ≥99% |
| PSA | 127.000 Ų | logp | 4.1 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
