CAS number：1350549-36-8 molecular formula：C25H34N6O4S
UNC1062 is a MERTK -selective tyrosine kinase inhibitor, reduces activation of MERTK-mediated downstream signaling, induces apoptosis in culture, reduces colony formation in soft agar, and inhibits invasion of melanoma cells. UNC1062 potently inhibits MERTK kinase activity (MERTK IC 50 =1.1 nM, Morrison K i =0.33 nM) and exhibits specificity within the TAM family (TYRO3 IC 50 =60 nM, AXL IC 50 =85 nM). Form:Solid
| Chinese alias | - | ||
| English alias | BDBM50055499 | AKOS000137114 | UNC1062 | UNC-1062 | US9744172, Compound UNC1062A | cis-4-(6-(Butylamino)-3-(4-(morpholinosulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)cyclohexan-1-ol | UNII-T7755XP5Y6 | 4-(6-(Butylamino)-3-(4-(morpholinosulfonyl)pheny | ||
| CAS number | 1350549-36-8 | molecular formula | C25H34N6O4S |
| molecular weight | 514.64 g/mol | Exact mass | - |
| PSA | 131.000 Ų | logp | 2.7 |
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