JAK-IN-11 是一种有效的选择性JAK抑制剂,详细信息请参考专利文献 WO2012122452A1 中的化合物 II。有潜力用于皮肤病 (如盘状红斑狼疮) 的研究。JAK-IN-11 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。
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R-348
CAS number:916742-11-5 molecular formula:C23H22FN5O4S
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 916742-11-5 | molecular formula | C23H22FN5O4S |
| molecular weight | 483.500 g/mol | Exact mass | ≥98% |
| PSA | 131.000 Ų | logp | 3.7 |
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