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R-348

CAS number:916742-11-5    molecular formula:C23H22FN5O4S

overview

compound introduction

JAK-IN-11 是一种有效的选择性JAK抑制剂,详细信息请参考专利文献 WO2012122452A1 中的化合物 II。有潜力用于皮肤病 (如盘状红斑狼疮) 的研究。JAK-IN-11 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。

Specs

Chinese alias-
English alias-
CAS number916742-11-5molecular formulaC23H22FN5O4S
molecular weight483.500 g/molExact mass≥98%
PSA131.000 Ųlogp3.7

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