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Testolone (RAD140)

CAS number:1182367-47-0    molecular formula:C20H16ClN5O2

overview

compound introduction

Information Testolone (RAD140) Testolone (RAD140) is a potent, orally bioavailable, nonsteroidal selective androgen receptor modulator with Ki value of 7 nM as well as good selectivity over other steroid hormone nuclear receptors. Targets Androgen Receptor 7 nM(Ki) In vivo The stability of RAD140 is high (t 1/2 > 2 h) in incubations with rat, monkey, and human microsomes, and it also has good bioavailability in rats (F = 27−63%) and monkeys (65−75%).

Specs

Chinese alias-
English aliass5275 | AKOS030526290 | 2-chloro-4-((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropylamino)-3-methylbenzonitrile | RAD140, | 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile | Ben
CAS number1182367-47-0molecular formulaC20H16ClN5O2
molecular weight393.83 g/molExact mass10mM in DMSO
PSA119.000 Ųlogp3.596

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