CAS number：722533-56-4 molecular formula：C30H38N2O2
Elacestrant (RAD1901) 是一种 estrogen receptor (ER) 降解剂 (SERD)，对 ERα 和 ERβ 的 IC50 值分别为 48 和 870 nM。Elacestrant 还能有效抑制 ER+ 乳腺癌细胞系在体内外的生长。 Elacestrant (RAD1901) is a selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo .
| Chinese alias | - | ||
| English alias | Elacestrant | ER306323 | ER-306323 | ORSERDU | GTPL12339 | F3308-1732 | AKOS032946378 | GLXC-26208 | WHO 10247 | (2R)-2-(2-(Ethyl-((4-(2-(ethylamino)ethyl)phenyl)methyl)amino)-4-methoxy-phenyl)tetralin-6-ol | ||
| CAS number | 722533-56-4 | molecular formula | C30H38N2O2 |
| molecular weight | 458.6 g/mol | Exact mass | - |
| PSA | 44.700 Ų | logp | 6.3 |
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