Enclomiphene ((E)-Clomiphene) 是一种有效的、可口服的非甾体雌激素受体 (estrogen receptor) 拮抗剂,具有抗雌激素作用。Enclomiphene 可用于卵巢功能障碍、睾酮缺乏、男性性腺功能减退症和 type 2 型糖尿病的相关研究。 在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 Enclomiphene citrate 通常具有更好的水溶性和稳定性。 Enclomiphene ((E)-Clomiphene) is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes.
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enclomiphene
CAS number:15690-57-0 molecular formula:C26H28ClNO
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| Chinese alias | 氯米芬 | ||
| English alias | HY-118861 | Enclomifene | Enclomifenum | RMI-16289 | trans-2-(4-(2-Chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine | Triethylamine, 2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)-, (E)- | Cisclomiphene | Enclomifene [INN] | Enclomiphene | ETHANAMINE, | ||
| CAS number | 15690-57-0 | molecular formula | C26H28ClNO |
| molecular weight | 405.96 g/mol | Exact mass | - |
| PSA | 12.500 Ų | logp | 7.2 |
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