Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. OLR1 / LOX1 was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX1 is induced by inflammatory stimuli and oxidative stimuli. This protein binds, internalizes, and degrades oxidized low-density lipoprotein. LOX1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2. In clinical, LOX1 is thought to be involved in the development of atherosclerotic lesions.
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Recombinant Human LOX-1/OLR1 Protein
CAS number：unknown molecular formula：
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compound introduction
Specs
| Chinese alias | 重组人LOX-1/OLR1蛋白 | 重组人 LOX-1/OLR1 蛋白 | ||
| English alias | CLEC8ASLOX1 | CLEC8A | C-type lectin domain family 8 member A | hLOX-1 | Lectin-like oxidized LDL receptor 1 | Lectin-like oxLDL receptor 1 | Lectin-type oxidized LDL receptor 1 | LOX1 | LOX-1 | LOX1ox LDL receptor 1 | LOXIN | OLR1 | oxidised low density | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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