CXCL5是一种小细胞因子，也被称为上皮中性粒细胞激活肽78(ena - 78)。这种蛋白质是在炎症细胞因子刺激细胞后产生的白细胞介素-1或肿瘤坏死因子。体外实验中，ENA-78(8-78)和ENA-78(9-78)使得中性粒细胞的趋化活性提高三倍。它们是由从外周血单核细胞分泌后的蛋白质水解产生的。重组人CXCL5 (5-78 a.a.)含有74个氨基酸，它是一个单一的非糖基化多肽链。人CXCL5有57%的氨基酸序列与小鼠和大鼠CXCL5相同。重组人ENA-78/CXCL5是一个8.1kDa大小的蛋白，含有74个氨基酸残基。 Purity >97% SDS-PAGE or HPLC analyses. Endotoxin level is Less than 0.1EU/µg . Function Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. Post-translational N-terminal processed forms ENA-78(8-78) and ENA-78(9-78) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. CXCL5 is a small cytokine also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). The protein is produced following stimulation of cells with the inflammatory cytokine interleukin-1 or tumor necrosis factor-alpha. In vitro, ENA-78 (8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. They are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Recombinant human CXCL5 (5-78 a.a.) contains 74 amino acids and it is a single non-glycosylated polypeptide chain. Human CXCL5 shares 57% amino acid sequence identity with mouse and rat CXCL5. Recombinant Human ENA-78/CXCL5 is an 8.1kDa protein containing 74 amino acid residues.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Recombinant Human CXCL5 Protein
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 上皮中性粒细胞激活肽78(ENA78)重组蛋白 | 重组人CXCL5蛋白 | 重组人 CXCL5 蛋白 | ||
| English alias | chemokine (C-C motif) ligand 5 | C-X-C motif chemokine 5 | CXCL5 | CXCL5/ENA-78 | ENA78 | ENA-78 | ENA-78(1-78) | Epithelial-derived neutrophil-activating protein 78 | Neutrophil-activating peptide ENA-78 | neutrophil-activating protein 78 | SCYB5ENA78 | | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
