Protein Function: CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.
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Recombinant Human CXADR Protein
CAS number：unknown molecular formula：
overview
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Specs
| Chinese alias | 重组人CXADR蛋白 | 重组人 CXADR 蛋白 | ||
| English alias | CAR4/6 | coxsackie virus and adenovirus receptor | coxsackie virus B receptor | coxsackievirus and adenovirus receptor | CVB3 binding protein | CVB3 BP | CVB3-binding protein | CXADR | HCAR | HCVADR | CAR10Coxsackievirus B-adenovirus receptor | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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