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Naphthoquine phosphate

CAS number:173531-58-3    molecular formula:C24H34ClN3O9P2

overview

compound introduction

Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia , including resistance of P. falciparum to Chloroquine. In Vivo The monkeys (Treated with Plasmodium knowlesi ) are treated i.g. once daily for 3 days with 6 or 10 mg/kg of Naphthoquine phosphate respectively. At 24 h after Naphthoquine phosphate administration, the parasite reduction rate is higher than 90%. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias磷酸萘酚喹
English alias2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol;phosphoric acid | M6M6AP4KAH | Naphthoquine phosphate | UNII-M6M6AP4KAH | F84830 | 1-Naphthalenol, 4-((7-chloro-4-quinolinyl)amino)-2-(((1,1-dimethylethyl)amino
CAS number173531-58-3molecular formulaC24H34ClN3O9P2
molecular weight605.94 g/molExact mass≥98%
PSA213.000 Ųlogp-

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