Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia , including resistance of P. falciparum to Chloroquine. In Vivo The monkeys (Treated with Plasmodium knowlesi ) are treated i.g. once daily for 3 days with 6 or 10 mg/kg of Naphthoquine phosphate respectively. At 24 h after Naphthoquine phosphate administration, the parasite reduction rate is higher than 90%. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Naphthoquine phosphate
CAS number:173531-58-3 molecular formula:C24H34ClN3O9P2
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| Chinese alias | 磷酸萘酚喹 | ||
| English alias | 2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol;phosphoric acid | M6M6AP4KAH | Naphthoquine phosphate | UNII-M6M6AP4KAH | F84830 | 1-Naphthalenol, 4-((7-chloro-4-quinolinyl)amino)-2-(((1,1-dimethylethyl)amino | ||
| CAS number | 173531-58-3 | molecular formula | C24H34ClN3O9P2 |
| molecular weight | 605.94 g/mol | Exact mass | ≥98% |
| PSA | 213.000 Ų | logp | - |
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