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(R)-Praziquantel-d11

CAS number:1399880-38-6    molecular formula:C19H13D11N2O2

overview

compound introduction

(R)-Praziquantel-d 11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer. In Vitro (R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:5-HT 2B Receptor Antischistosomal

Specs

Chinese alias(R)-吡喹酮-d11
English alias-
CAS number1399880-38-6molecular formulaC19H13D11N2O2
molecular weight323.47 g/molExact mass≥99%
PSA-logp-

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