SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infe Appearance:Solid In Vitro:SPR741 potentiates antibiotics that are substrates of the AcrAB-TolC efflux pump in E. coli , effectively circumventing the contribution of this pump to intrinsic antibiotic resistance. The intrinsic resistance of E. coli to certain antibiotics that is me In Vivo:SPR741 has the ability to permeabilize the outer membrane of Gram-negative bacteria, thus sensitizing them to hydrophobic antibiotics. SPR741 has a significantly safety profile of compared to that of polymyxin B, which suffers severe, dose-limiting nephro Biological Activity:SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacteria infe
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SPR741 acetate
CAS number：unknown molecular formula：C46H77N13O15
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| Chinese alias | SPR741醋酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C46H77N13O15 |
| molecular weight | 1052.18 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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