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7-((Benzo[d]thiazol-2-ylamino)(4-(difluoromethoxy)phenyl)methyl)quinolin-8-ol

CAS number:446826-86-4    molecular formula:C24H17F2N3O2S

overview

compound introduction

KIN1400 是一种有效的IRF3激活剂。KIN1400 可触发 IRF3 依赖性先天免疫抗病毒基因(RIG-I、MDA5、IFIT1和Mx1)和IFN-β表达。KIN1400 抑制WNV和DV,这是Flaviviridae和Flavivirus属的两种蚊媒成员。KIN1400 还抑制HCV复制。 KIN1400 通过 MAVS-IRF3 轴诱导先天抗病毒免疫。

Specs

Chinese alias-
English alias-
CAS number446826-86-4molecular formulaC24H17F2N3O2S
molecular weight449.47 g/molExact mass≥98%
PSA95.500 Ųlogp6.7

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