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18-Methoxycoronaridine, (+/-)-

CAS number:188125-42-0    molecular formula:C22H28N2O3

overview

compound introduction

Zolunicant (MM-110) 是一种有效的烟碱 α吗啡、甲基苯丙胺、尼古丁和乙醇等几种3β4 受体(nicotinic α3β4 receptors)的抑制剂,其IC50为 0.90 μM。在大鼠模型中,Zolunicant 能降低吗啡、甲基苯丙胺、尼古丁和乙醇等成瘾剂的自我给药能力。Zolunicant 可以被用于研究多种形式的活性分子滥用。Zolunicant 对亚马逊利什曼原虫具有显著的杀利什曼原虫的作用。

Specs

Chinese alias-
English alias-
CAS number188125-42-0molecular formulaC22H28N2O3
molecular weight368.5 g/molExact mass≥99%
PSA54.600 Ųlogp2.9

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