BIT-225 是 Vpu 蛋白的抑制剂,通过阻断 Vpu 离子通道来抑制HIV-1的释放,在单核细胞衍生的巨噬细胞中的EC50为 2.25 μM,且无明显的细胞毒性 (TC50为 284 μM)。
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2-Naphthalenecarboxamide, N-(aminoiminomethyl)-5-(1-methyl-1H-pyrazol-4-yl)-
CAS number:917909-71-8 molecular formula:C16H15N5O
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 917909-71-8 | molecular formula | C16H15N5O |
| molecular weight | 293.320 g/mol | Exact mass | ≥98% |
| PSA | 99.300 Ų | logp | 2 |
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