CAS number：1204144-28-4 molecular formula：C21H21N3O2S
AZD1208是口服活性的PIM高选择性抑制剂，对Pim1, Pim2, 和 Pim3的IC50分别为5 nM, 25 nM 和 16 nM。 AZD1208 is a potent, and orally available Pim kinase inhibitor with IC50 of 0.4 nM, 5 nM, and 1.9 nM for Pim1, Pim2, and Pim3 in cell-free assays, respectively.
| Chinese alias | - | ||
| English alias | AZD 1208 [WHO-DD] | Q27074698 | FT-0633869 | J-013789 | HY-15604 | S98NFM1378 | SW219766-1 | 1204144-28-4 | AZ-1208 | (R,Z)-5-((2-(3-Aminopiperidin-1-yl)biphenyl-3-yl)methylene)thiazolidine-2,4-dione | AZD1208 | AZD-1208 | NSC776066 | NSC-776066 | (R,Z)-5 | ||
| CAS number | 1204144-28-4 | molecular formula | C21H21N3O2S |
| molecular weight | 379.48 g/mol | Exact mass | - |
| PSA | 101.000 Ų | logp | 3.600 |
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