compound introduction
Oprozomib (ONX 0912)是一种口服生物有效的抑制剂，抑制20S proteasome（20S蛋白酶体）β5/LMP7的CT-L活性，IC50为36 nM/82 nM。 Oprozomib (ONX 0912) is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM.
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Oprozomib (ONX 0912)
CAS number：935888-69-0 molecular formula：C25H32N4O7S
overview
Specs
| Chinese alias | 奥泼佐米 | ||
| English alias | ONX-0912 | PR-047 | J-690398 | N-((S)-3-methoxy-1-(((S)-3-methoxy-1-(((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methylthiazole-5-carboxamide | SWZXEVABPLUDIO-WSZYKNRRSA-N | DTXSID201025950 | ||
| CAS number | 935888-69-0 | molecular formula | C25H32N4O7S |
| molecular weight | 532.61 g/mol | Exact mass | - |
| PSA | 176.000 Ų | logp | 1.1 |
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