Thalidomide-O-amido-C8-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。可用于合成 PROTAC 分子。 Thalidomide-O-amido-C8-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs。
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Thalidomide-O-amido-C8-NH2 hydrochloride
CAS number:2415263-07-7 molecular formula:C23H30N4O6.HCl
overview
compound introduction
Specs
| Chinese alias | N-(8-氨基辛基)-2-[[2-(2,6-二氧代-3-哌啶基)-2,3-二氢-1,3-二氧代-1H-异吲哚-4-基]氧基]-乙酰胺盐酸盐 | ||
| English alias | N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide hydrochloride | ||
| CAS number | 2415263-07-7 | molecular formula | C23H30N4O6.HCl |
| molecular weight | 494.97 g/mol | Exact mass | ≥95%(HPLC) |
| PSA | - | logp | - |
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