compound introduction
AS1842856 是具有细胞可透性的抑制剂，抑制Foxo1的转录活性，IC50=33 nM。AS1842856 可直接结合活化的Foxo1，但不结合Ser256位磷酸化的Foxo1。AS1842856 可抑制自噬。
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AS 1842856
CAS number：836620-48-5 molecular formula：C18H22 FN3O3
overview
Specs
| Chinese alias | 5-氨基-7-(环己基氨基)-1-乙基-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸 | ||
| English alias | 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | ||
| CAS number | 836620-48-5 | molecular formula | C18H22 FN3O3 |
| molecular weight | 347.39 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 95.700 Ų | logp | 3.600 |
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