compound introduction
XL388是一种高效的，ATP竞争性的mTOR选择性抑制剂，IC50为9.9 nM，比作用于紧密相关的PI3K激酶选择性高1000倍。
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XL388
CAS number：1251156-08-7 molecular formula：C23H22FN3O4S
overview
Specs
| Chinese alias | [7-(6-氨基-3-吡啶基)-2,3-二氢-1,4-苯并氧氮杂卓-4(5H)-基][3-氟-2-甲基-4-(甲基磺酰基)苯基]-甲酮 | ||
| English alias | A12395 | XL388 | XL-388 | (7-(6-aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methylsulfonyl)phenyl)methanone | (7-(6-Aminopyridin-3-yl)-3,5-dihydro-2H-1,4-benzoxazepin-4-yl)-(3-fluoro-2-methyl-4-methylsulfonylphenyl)m | ||
| CAS number | 1251156-08-7 | molecular formula | C23H22FN3O4S |
| molecular weight | 455.5 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 2.500 |
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