IDO5L是高活性IDO1抑制剂,IC50为67 nM。 INCB024360 analogue is a potent, competitive IDO1 (indoleamine-(2,3)-dioxygenase) inhibitor with IC50 of 67 nM A competitive indoleamine 2,3-dioxygenase inhibitor
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INCB024360 analogue
CAS number:914471-09-3 molecular formula:C9H7ClFN5O2
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compound introduction
Specs
| Chinese alias | INCB024360 类似物 | ||
| English alias | NSC785571 | NSC-785571 | SCHEMBL19654569 | UNII-2HR315841W | 914471-09-3 (INCB14943) | BDBM50300305 | (4E)-4-[(3-chloro-4-fluoroanilino)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine | HMS3653H15 | US10202388, Ref. B | 4-Amino-N'-(3-chloro-4-fluorophenyl)-N | ||
| CAS number | 914471-09-3 | molecular formula | C9H7ClFN5O2 |
| molecular weight | 271.64 g/mol | Exact mass | 10mM in DMSO |
| PSA | 110.000 Ų | logp | 1.600 |
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