RO495 是一种有效的非受体酪氨酸蛋白激酶2抑制剂。 RO495 is an effective non receptor tyrosine protein kinase 2 inhibitor. Information RO495 RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2) . Targets TYK2 Explanation RO495, a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays;
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RO495
CAS number:1258296-60-4 molecular formula:C17H14Cl2N6O
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Specs
| Chinese alias | - | ||
| English alias | Benzamid | N-[2-[(2-amino-6-methyl-4-pyrimidinyl)amino]-4-pyridinyl]-2,6-dichloro- | ||
| CAS number | 1258296-60-4 | molecular formula | C17H14Cl2N6O |
| molecular weight | 389.24 g/mol | Exact mass | ≥98% |
| PSA | 106.000 Ų | logp | 3.699 |
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