Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC 50 value of 24.6 μM for rat liver microsomal ACAT activity In Vitro Glabrol (Compound 1) decreases cholesteryl ester formation with an IC 50 value of 26.0 μM in HepG2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:ratACAT 24.6 μM (IC 50 )
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Glabrol
CAS number:59870-65-4 molecular formula:C25H28O4
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| Chinese alias | 格拉布洛尔 | ||
| English alias | - | ||
| CAS number | 59870-65-4 | molecular formula | C25H28O4 |
| molecular weight | 392.49 g/mol | Exact mass | ≥99% |
| PSA | 66.800 Ų | logp | 6.000 |
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