Purity: >95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Cyclophilin B (SCYLP, CyPB, and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, it mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization and facilitating the activity of additional chaperones. The human CyPB precursor is 216 amino acids (aa) in length. It contains a 25 aa signal sequence plus a 191 aa mature region. There is a partial heparin-binding sequence (aa 27‑34), a PPIase domain (aa 47‑204), and a C-terminal ER retention motif (aa 213‑216). Over aa 34‑216, the human and mouse sequences are 95% aa identical.
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Recombinant Human Cyclophilin B Protein
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 重组人Cyclophilin B蛋白 | 重组人Cyclophilin B蛋白 | 重组人类环丝氨酸蛋白酶B蛋白 | ||
| English alias | Cyclophilin B | cyclophilin-like protein | CYPB | CYPBEC 5.2.1.8 | CYP-S1 | MGC2224 | OI9MGC14109 | peptidyl-prolyl cis-trans isomerase B | peptidylprolyl isomerase B (cyclophilin B) | PPIase B | PPIB | Rotamase B | S-cyclophilin | SCYLP | Cyclophilin B | | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无载体 |
| PSA | - | logp | - |
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