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Recombinant Canine CD14 Protein

CAS number:unknown    molecular formula:

overview

compound introduction

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL-.

Specs

Chinese alias重组狗CD14蛋白 | 重组犬CD14蛋白
English aliasCD14 | CD14 molecule | Monocyte differentiation antigen CD14 | Myeloid cell-specific leucine-rich glycoprotein
CAS numberunknownmolecular formula
molecular weight-Exact mass无动物源
PSA-logp-

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