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DSPE-PEG-PDP

CAS number:unknown    molecular formula:

overview

compound introduction

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) and PDP conjμgated Polyethylene Glycol is a heterobifunctional PEG derivative that can undergo reaction with sulfhydryl group. DSPE PEG is an 18 carbon phospholipid PEG conjμgate which has both hydrophilicity and hydrophobility. PDP (pyridyldithiol propionate) is reactive toward free thiol group to form cleavable disulfide bond. Pegylated phospholipids are excellent liposome formation materials that can be used for drμg delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drμgs. These materials can also be used for targeted drμg delivery by modifying their surfaces with targeting ligands such as antibodies, peptides. 1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) and PDP conjugated Polyethylene Glycol is a heterobifunctional PEG derivative that can undergo reaction with sulfhydryl group. DSPE PEG is an 18 carbon phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. PDP (pyridyldithiol propionate) is reactive toward free thiol group to form cleavable disulfide bond. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

Specs

Chinese alias-
English alias-
CAS numberunknownmolecular formula
molecular weight-Exact massMW 3400 Da
PSA-logp-

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