(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 5 个单元 PEG linker。
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VH 032 amide-PEG5-acid
CAS number:2172820-14-1 molecular formula:C36H54N4O11S
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compound introduction
Specs
| Chinese alias | (S)-21-(((2S,4R)-4-羟基-2-((4-(4-甲基噻唑-5-基)苄基)氨基甲酰基)吡咯烷-1-羰基)-22,22-二甲基-19 -oxo-4,7,10,13,16-五氧杂-20-氮杂三酸 | VH 032 酰胺-PEG5-酸 | ||
| English alias | (S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanoic acid | (S,R,S)-AHPC-PEG5-COOH | VH032-PEG5-COOH | VHL Ligand-Linker Conjugates 16 | ||
| CAS number | 2172820-14-1 | molecular formula | C36H54N4O11S |
| molecular weight | 750.91 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
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