氢溴酸高乌甲素 (Lappaconitine hydrobromide)是一种天然生物碱类化合物，具有抗心律失常的功效。 产品应用： Lappaconite Hydrobromide（Lappaconite HBr）是从高乌头中分离的生物碱，并显示出抗炎作用。在中国，Lappaconite HBr被用做止痛药物。高乌头属于毛茛科，在中国传统医学中，它被广泛用作抗风湿和镇痛剂。 Information Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. In vitro Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects. Its absorption percentage in rat stomachs after administration was 9.67%.The absorption percentages at duodenum,jejunum,ileum and colon were 19.61%,11.83%,12.95% and 9.51%, respectively.When the concentration was raised from 10 mg/L to 40 mg/L, the uptake of lappaconite hydrobromide was linearly increased,whereas the absorption rate constant kept at the same level. In vivo LD50: Mice 10.5mg/kg (i.p.); Rats 9.9mg/kg (i.p.) Cell Data cell lines： HPAF-II, PaTu 8988S, and Capan-2 cells Concentrations： Incubation Time： Powder Purity:≥95%
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Lappaconite HBr
CAS number：97792-45-5(DMSO) molecular formula：C32H44N2O8·HBr
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | Aconitane-4,8,9-triol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], hydrobromide (1:1), (1α,14α,16β)- | ||
| CAS number | 97792-45-5(DMSO) | molecular formula | C32H44N2O8·HBr |
| molecular weight | 665.61 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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