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CL2A

CAS number:2616704-22-2    molecular formula:C50H79N9O16

overview

compound introduction

CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker Form:Viscous liquid IC50& Target:Cleavable

Specs

Chinese alias-
English alias-
CAS number2616704-22-2molecular formulaC50H79N9O16
molecular weight1062.21 g/molExact mass≥97%
PSA-logp-

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