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Duocarmycin TM

CAS number:157922-77-5(DMSO)    molecular formula:C25H23ClN2O5

overview

compound introduction

Duocarmycin TM (CBI-TMI) is a potent antitumor antibiotic . Duocarmycin TM induces a sequence-selective alkylation of duplex DNA. In Vitro Duocarmycin TM (60 μM; 4 d; BJAB and WSU-DLCL2 cells) is a cytotoxic agent that inhibits the proliferation of tumor cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: BJAB and WSU-DLCL2 cells Concentration: 60 μM Incubation Time: 4 days Result: Inhibited the proliferation of tumor cells with IC 50 values of 0.153 μM and 0.079μM for BJAB and WSU-DLCL2 cells, respectively. IC50& Target:Duocarmycins

Specs

Chinese alias多卡米星
English alias-
CAS number157922-77-5(DMSO)molecular formulaC25H23ClN2O5
molecular weight466.91 g/molExact mass10mM in DMSO
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