DM4-SMe is a metabolite of antibody-maytansin conjugates (AMCs) and a tubulin inhibitor, and also a cytotoxic moiety of antibody-drug conjugates (ADCs) , which can be linked to antibody through disulfide bond or stable thioether bond. DM4-SMe inhibits KB cells with an IC 50 of 0.026 nM IC50& Target:Maytansinoids
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DM4-SMe
CAS number:796073-68-2(DMSO) molecular formula:C39H56ClN3O10S2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 796073-68-2(DMSO) | molecular formula | C39H56ClN3O10S2 |
| molecular weight | 826.46 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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