CMPF是呋喃脂肪酸的内源性代谢产物，天然存在于磷脂中，与白蛋白高度结合。CMPF的作用是抑制细胞运输和随后的甲状腺素（T4）脱碘。此外，CMPF通过取代竞争性T4分子间接结合白蛋白而发挥作用。相信CMPF通过增加竞争性结合分子例如游离脂肪酸的血清浓度来抑制这种结合。此外，CMPF是一种有机磷酸酯BChE（胆碱酯酶）抑制剂。 CMPF is an endogenous metabolite of furan fatty acids, naturally found in phospholipids, that is highly albumin-bound. CMPF functions to inhibit cellular transport and subsequent deiodination of thyroxine (T4). In addition, CMPF functions by displacing competitive T4 molecules from indirectly binding to albumin. It is believed that CMPF inhibits this binding by increasing the serum concentration of competitive binding molecules such as free fatty acids. Furthermore, CMPF is an organophosphate BChE (cholinesterase) inhibitor. Application： CMPF is a drug-binding inhibitor which is also a constituent of urine. CMPF can inhibit specific T4 binding in serum by increasing the free concentration of direct competitors.
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3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid
CAS number：86879-39-2 molecular formula：C12H16O5
overview
compound introduction
Specs
| Chinese alias | 丙基呋喃酸 | ||
| English alias | CMPF | 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid, analytical standard | 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC | CMPF | 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid | 2-FURANPROPIONIC ACID, 3-CARBOXY-4-METHYL-5-PROPYL- | AKOS030255099 | | ||
| CAS number | 86879-39-2 | molecular formula | C12H16O5 |
| molecular weight | 240.25 g/mol | Exact mass | ≥98% |
| PSA | 87.700 Ų | logp | 1.9 |
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MSDS
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86879-39-2 | 3-Carboxy-4-methyl-5-propyl-2-furanpropionic acid.pdf
